As far as I can tell, you can only set the validation/deployments settings as a whole.
“Override Save All Action”
“Deploy all Modified Files”
“Deploy on Save”
It’d be great if we could set these settings per connection as there might be some sandboxes we’d be willing to do this (dev sandbox) versus some we don’t want to inadvertently deploy to (stage). This would allow the user to switch connections (if they need to retrieve configured metadata, non-development work) and not worry about pushing their code accidentally.