+import requests

+import sys

+

+URL = "http://biosig.unimelb.edu.au/mmcsm_ppi/api/manual"

+

+def main(args):

+    pdb_file = args.pdb_file

+    mutations_list = args.mutations_list

+

+    files_to_submit = {"pdb_file": pdb_file,"mutations_list": mutations_file}

+

+    req = requests.post(URL, files=pdb_to_submit)

+    print(req.json())

+    return True

+

+if __name__ == "__main__":

+    parser = argparse.ArgumentParser(description='Job submission for manual input prediction - mmCSM-PPI')

+    parser.add_argument('--pdb_file', dest='pdb_file', type=file, help='PDB file', required=False, default=None)

+    parser.add_argument('--mutations_list', dest='mutations_list', type=file, help='Mutation list file. One entry per line. Mutations must be separated by a semi-colon (;). E.g.: A E346K;A T118P')

+

+    args = parser.parse_args()

+    if args.pdb_file == None:

+        print('usage: main.py [-h] [--pdb_file PDB_FILE]')

+        print('[--mutations_list MUTATION]')

+        print('main.py: error: missing arguments: Please provide --pdb_file')

+        sys.exit(1)