Requirements: ocaml 3.11.2 or newer findlib camidl python 2.x (>= 2.6) library and header omake OMyMakefile of omy package at https://bitbucket.org/camlspotter/omy, if not included in the source perl :-) To compile: Create OMakeroot by omake --install . Do NOT overwrite OMakefile! Make sure you have OMyMakefile. Set PREFIX environment variable: % export PREFIX=/usr (in bash) If you are enough lucky: % omake just do the build. % omake install installs opycaml as an ocamlfind package. Reinstall requires ocamlfind remove opycaml beforehand.