This proposal involves two MAPINFO flags. The flag "resetplayerinventory" would clear the player's inventory and reset it to the starting items for the player class, and the flag "removeinventory <item>, <quantity>" would remove a specific item from the player's inventory. They could be used together or separately. The following:
resetplayerinventory removeinventory "Pistol", 1 removeinventory "Clip", 99
would take away all of the player's weapons and ammo, leaving him with only a knife.