bw = BigWigFile(open('xxx.bw', 'r'))
bw.query(chrStr, start, end, 1)
when end - start > 4096, the result is not correct.
I compared the results with bigWigSummary, when 'end - start' <=4096, 'mean' field using bw.query is exactly the same as bigWigSummary. when 'end - start' > 4096, the mean value using query suddenly becomes zero.