I am trying to using mixOmics to integrate transcriptomics and metabolomics data. How would one decide on the appropriate design matrix to input for the block.splsda function. I see there is posting in the FAQ section under the mixOmics site http://mixomics.org/faq/data-input/.
Does that mean i have to run spls function to figure out the correlation structure between the two datasets and use that value in creating a design matrix.
Thanks for any one making suggestions.