Need to validate the significance tests in testDiversity
Issue #11
new
Does low sequence counts and/or low clone size (low clone size variance) lead to inflated significance scores from testDiversity()
? This needs to be tested and corrected if that's the case.
Comments (2)
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reporter -
reporter Low sequence counts (<1000) may still be a problem. We might need to redo the inference of the complete clonal abundance distribution with each bootstrap realization or something.
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Swapped this for the Chao et al, 2014 bootstrap from inferred complete abundance distribution. This should resolve the inflation, but it still needs to be tested.