changeo /

Filename Size Date modified Message
bin
changeo
docs
tests
1.4 KB
Added tag Version 0.3.9 - DefineClones Brownbag for changeset 4ba853818a72
4.3 KB
Fixes for release.
20.1 KB
Updated license to CC BY-SA 4.0.
96 B
Fixed MANIFEST.
16.5 KB
BuildTrees doucmentation.
947 B
Minor.
186 B
1. Updated NEWS with all v0.4 changes to date.
96 B
1. Added `-y` argument to ConvertDb-genbank to allow argument definitions via yaml file.
2.9 KB
Add more keywords to setup.

Change-O - Repertoire clonal assignment toolkit

Change-O is a collection of tools for processing the output of V(D)J alignment tools, assigning clonal clusters to immunoglobulin (Ig) sequences, and reconstructing germline sequences.

Dramatic improvements in high-throughput sequencing technologies now enable large-scale characterization of Ig repertoires, defined as the collection of trans-membrane antigen-receptor proteins located on the surface of B cells and T cells. Change-O is a suite of utilities to facilitate advanced analysis of Ig and TCR sequences following germline segment assignment. Change-O handles output from IMGT/HighV-QUEST and IgBLAST, and provides a wide variety of clustering methods for assigning clonal groups to Ig sequences. Record sorting, grouping, and various database manipulation operations are also included.