changeo /

Filename Size Date modified Message
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Added tag Version 0.3.9 - DefineClones Brownbag for changeset 4ba853818a72
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Fixes for release.
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Updated license to CC BY-SA 4.0.
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BuildTrees doucmentation.
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1. Updated NEWS with all v0.4 changes to date.
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1. Added `-y` argument to ConvertDb-genbank to allow argument definitions via yaml file.
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Add more keywords to setup.

Change-O - Repertoire clonal assignment toolkit

Change-O is a collection of tools for processing the output of V(D)J alignment tools, assigning clonal clusters to immunoglobulin (Ig) sequences, and reconstructing germline sequences.

Dramatic improvements in high-throughput sequencing technologies now enable large-scale characterization of Ig repertoires, defined as the collection of trans-membrane antigen-receptor proteins located on the surface of B cells and T cells. Change-O is a suite of utilities to facilitate advanced analysis of Ig and TCR sequences following germline segment assignment. Change-O handles output from IMGT/HighV-QUEST and IgBLAST, and provides a wide variety of clustering methods for assigning clonal groups to Ig sequences. Record sorting, grouping, and various database manipulation operations are also included.