- changed status to resolved
Make denominator in mutation frequency calculations based on informative positions
Issue #26
resolved
calcObservedMutations()
and calcExpectedMutations()
should account for non-informative positions when determining the sequence length (denominator) for mutation frequency calculations. Should only include positions that are informative (eg, ACGT, but probably including the extended ambiguous alphabet) in both the input and germline sequence.
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Resolved!