Combining technical replicates and different enzymes

Issue #20 new
Anonymous created an issue

I have some doubts on how to combine different technical replicates and enzymes to get a final higher-resolution matrice. In which case do you advice to do so ? If so, at which step of the analysis should I combine them and how?

Thanks a lot for your help!

Comments (1)

  1. Ilya Flyamer

    I figured out that there is a

    fragmentHiC.HiCdataset.merge()
    

    method which does exactly what you are asking about for technical replicates. Not sure about different enzymes though, I guess it won't work like that, and you have to just sum two heatmaps.

  2. Log in to comment