Source

pypy / pypy / doc / config / translation.check_str_without_nul.txt

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If turned on, the annotator will keep track of which strings can
potentially contain NUL characters, and complain if one such string
is passed to some external functions --- e.g. if it is used as a
filename in os.open().  Defaults to False because it is usually more
pain than benefit, but turned on by targetpypystandalone.