I shouldn't get emailed for issues that I myself closed or commented on. I already know what happened (I did the action) so no notice is required.
It adds a lot of noise and makes each of the emails less important and more likely to be ignored.
On a related note it would also be great if the content of the issue were highlighted in some way in the email. Right now the emails themselves are quite noisy. Its difficult to read through quickly to get to what the issue is actually about, wether its new, updated or closed and who is actually in charge of said issue.